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Treatments

Corneal Collagen Crosslinking

The procedure aims to strengthen the cornea of the eye by application of vitamin B2 (riboflavin), followed by treatment with ultraviolet A (UV-A) light.

It is often recommended when the cornea needs strengthening; especially for the treatment of keratoconus, or where there is an unstable cornea.

It is a non-surgical method utilising a UV-A light source, which is delivered onto the cornea, together with a chemical mix largely made up of riboflavin for strengthening the collagen fibres within the corneal structure. The combination of the UV-A light and the riboflavin creates a joining or bonding of the chemical structures within the cornea.

This comparatively simple procedure has been shown in laboratory and clinical studies to increase the amount of collagen cross-linking in the cornea and subsequently strengthen the cornea. There are published European studies, to show that this Cross Linking procedure has been proven safe and effective in patients with few side effects reported. Additionally, retreatment is an option at a later date if required.

Cross-linking therapy is being used for a number of diseases of the cornea and is proving a useful treatment in conjunction with other surgical techniques such as Intacs and refractive laser surgery.

However cross linking is not for everybody. The first requirement is to ensure that the thickness of the cornea is adequate for the treatment. Special non-invasive measuring devices are used by your specialist to accurately and quickly take these readings.

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Corneal Collagen Crosslinking

At a glance

Treatment

Frequently asked questions

The Cross Linking procedure takes between 10 and 30 minutes and may be either conducted in an Operating theatre or a special “clean” room.

The eye is anaesthetized with drops. Riboflavin eye drops are applied for the initial 10-30 minute period. After this, application of the ultraviolet light is commenced for between 4-30 minutes, with further application of the Riboflavin eye drops.

At the end of the procedure, the eye is will gently cleaned with a special solution and a protective bandage contact lens is placed for a period of 1-2 weeks.

Corneal cross linking works by increasing the number of bonds between collagen fibres. It can be performed as a staged procedure with wavefront-guided LASEK (surface excimer laser treatment). After cross linking the corneal shape can improve with a significant increase in mechanical stiffness of the cornea.

Mr Jayaswal has an excellent track record for achieving a very low complication rate with his surgery. However all procedures carry some risk.

When performed by a skilled surgeon with modern equipment, corneal cross-linking has a low risk of serious complication. Possible complications include prolonged healing of the corneal epithelium with delayed recovery of vision, corneal stromal scarring or melting and failure of the cross-linking to increase corneal strength and stability. Overall the risk to benefit ratio for cross-linking is generally considered good and cross-linking should be considered where there is weakening of the cornea and progression of warpage.

Lesser but common issues may include some degree of dry eye or blepharitis (irritation of the eyelids) in the healing period.

There is some degree of unpredictability in outcome as with any corneal surgery. You should read all the information given to you about possible complications before undergoing any treatment.

Risks of the procedure (to all structures of the eye) are minimal. The main risks are infection, and inflammation of the cornea after surgery but these risks are extremely low. Rigorous observation of the indications and contraindications has been conducted.

After Cross Linking, patients often experience:

  • Post-operative pain and sensation of foreign body in the eye for 24-48 hours after treatment until re-epithelialisation is complete
    Watering of the eye for 24-72 hours after treatment
    Transient corneal oedema with visual blurring for 30-60 days after treatment
    Corneal haze usually occurs but clears in the first 8 weeks

Price

From £ 1850

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What our patients say...

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Christine Ayling
Christine Ayling
30/01/2023
From the first consultation through to the final follow up appointment I cannot fault the whole experience. Rakesh Jayaswal put me at my ease, was friendly, professional & caring. I cannot recommend him highly enough.
David Debono
David Debono
11/01/2023
I cannot fault my experience with LaserVision. Results are amazing Care and support 10 out of 10 Cost…..definitely worth it, 100% Thanks to Rakesh and team for everything, I could not be happier.
Angela Corbett
Angela Corbett
14/12/2022
I received outstanding care and support throughout my treatment that went above and beyond my expectations in every aspect. All of my fears were allayed in a caring and sensitive way, that inspired my confidence to go ahead with the lens replacement surgery. The outcome is amazing. I am glasses free with excellent vision. I cannot thank Rakesh and his team enough. His kindness and skill has changed my life. I highly recommend Rakesh and his team at Laservision.
Mark Stradling
Mark Stradling
14/11/2022
Not only is Rakesh a very nice man, he is a master of his craft and has demonstrated a keen desire to ensure I am truly happy with my new eyes. Sometimes things dont go precisely to plan and it is at times like this some might create reasons to run away. Not Rakesh or anyone on the Laser Vision team. They are incredibly dedicated to customer service and my well being, ultimately ensuring that one of my most important senses, will be vastly improved from it's former blurred state and enable me to live a full colorful life, for the rest of my life.
Mark Bailey
Mark Bailey
12/11/2022
Friendly, professional service, really pleased with surgery result.
Keely Green
Keely Green
10/11/2022
Wonderful service from the 1st appointment. Caring staff and my options were explained to me thoroughly in great detail. The operation was painless and happened in no time at all. The staff on the day were attentive to all my needs. The after care was impeccable. Having lens replacement surgery was the best decision I could make. It has changed my life and being free of glasses is amazing. Rakesh and his team at Laservision have been so kind and so professional I can't recommend them enough.
Bernadette Grima
Bernadette Grima
10/10/2022
I've had cataracts and laser with Mr Rakesh Jayaswal this year. I was delighted with his help and re-assurance throughout both procedures and cannot recommend him and his team highly enough. Always with a friendly smile and very patient in answering all my queries. All the team, including Vicky and the admin ladies, were a joy to deal with. I highly recommend LaserVision and would certainly go back if I need any further treatment in the future.
John Robinson
John Robinson
11/10/2021
Very well looked after from the first consultation. Needn't have worried about the painless lens replacement surgery and now I have perfect long distance and short vision for the first time in over fifty years. A huge thanks to Rakesh and all of his team from a very satisfied patient.
Helen McDowall
Helen McDowall
11/09/2020
From first consultation, through surgery, to discharge- review, lens replacement surgery and aftercare has been seamless. I have always felt well cared- for and supported even throughout 2020 when Covid19 moved the goal posts! Rakesh and his team are ultimate professionals in their field and really believe in what they're doing. They are just lovely human- beings. This surgery liberated my life from contact lenses and glasses after 45 years. Thankyou ....
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0800 024 8888

rakesh.jayaswal@laservision.co.uk

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Prema Clinic
Compass Rd
Portsmouth
PO6 4RP

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